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Researchers Combining FDM 3D Printing with Hot-Melt Extrusion for Drug Delivery Systems

Researchers Combining FDM 3D Printing with Hot-Melt Extrusion for Drug Delivery Systems

Written by David

November 19, 2018

We’ve often seen 3D printing used to make drug delivery systems , but a trio of researchers from the University of Sussex are combining FDM technology with something called Hot-Melt Extrusion, or HME, to do the same. Deck Khong Tan, Mohammed Maniruzzaman, and Ali Nokhodchi, from the university’s Pharmaceutics Research Laboratory, recently published a paper, titled “ Advanced Pharmaceutical Applications of Hot-Melt Extrusion Coupled with Fused Deposition Modelling (FDM) 3D Printing for Personalised Drug Delivery ,” that details their work. The abstract reads, “The most common 3D printing technology is called the Fused Deposition Modelling (FDM) which utilises thermoplastic filaments as a starting material, then extrudes the material in sequential layers above its melting temperature to create a 3D object. These filaments can be fabricated using the Hot-Melt Extrusion (HME) technology. The advantage of using HME to manufacture polymer filaments for FDM printing is that a homogenous solid dispersion […]

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