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Newcastle University researchers 3D bioprint artificial cornea with self-assembling 4D biomaterials

Written by David

February 13, 2019

Corneal transplantation is one of the primary treatments for loss of corneal function, but only one in 70 people who need corneal transplants receive them, leaving some 12.5 million people suffering from vision loss because there simply aren’t enough corneal donors to go around. Attempts to replicate the perfectly-spherical, collagen-based protective layer of the eye have come up short. But last year we reported on a 3D bioprinted cornea out of Newcastle University that looked (pun intended) very promising. Now, Martina Miotto, a post-doctoral researcher in tissue engineering at the same Newcastle University has created a self-assembling cornea fabricated from 4D biomaterials. 4D biomaterials are materials comprised of biocompatible substrates and living tissue cells that change shape, composition, and/or function when exposed to specific external stimuli. Collagen gels that contain corneal cells (CCCGs) exhibit a contracting shrinkage, and Miotto and her team previously discovered that the presence of peptide […]

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