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Engineers Grow Prevascularized Tissue for Cardiac Patches

Engineers Grow Prevascularized Tissue for Cardiac Patches

Written by David

March 29, 2019

Patching up a heart needs the help of tiny blood vessels. Aligning dense vascular structures in engineered cardiac patches can help patients recover from a heart attack. A team led by Feng Zhao, associate professor of biomedical engineering at Michigan Technological University, recently published two new papers on best practices in engineering prevascularized tissues. The team’s research paper, published in Theranostics ( DOI: 10.7150/thno.29552 ), focuses on developing a stem cell cardiac patch made with tissue engineered with tiny blood vessels to be like real heart muscle. Their review paper, published in Acta Biomaterialia ( DOI: 10.1016/j.actbio.2019.03.016 ), examines the pros and cons of six innovative strategies for aligning the microvessels in engineered tissues. Bioengineered Tissue, Organized Vasculature The vascular system brings nutrients and oxygen to tissues; important ingredients for successful healing following an organ transplant, heart surgery or skin graft. Microvascular structures, which are capillary-like microvessels, are particularly […]


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