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Chinese researchers develop all-aqueous 3D bioprinting method for regenerative medicine

Written by David

November 6, 2019

Scientists from the School of Medicine, Shenzhen University , China, have developed a Freeform Reconfigurable Embedded All-Liquid (FREAL) bioprinting method to create 3D architectures microstructures.


Through compartmentalized bioink with living cells, the 3D printed tissue constructs can facilitate medical models, organ-on-chips, thus furthering regenerative medicine research.


“This offers unique opportunities and powerful tools since limitless formulations can be designed from among a breadth of natural and synthetic hydrophilic polymers to mimic tissues,” states a paper published in Advanced Materials. “This printing approach may be useful to engineer biomimetic, dynamic tissue-like constructs for potential applications in drug screening, in vitro tissue models, and regenerative medicine.”


Aqueous structures created using FREAL printing. Photo via Shenzhen University. Freeform reconfigurable embedded all-liquid bioprinting According to the researchers, aqueous or water-based microstructures are challenging to create, handle, and preserve as its surfaces are prone to shrink into spherical shapes with minimum surface areas. […]

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