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Bioprinting 101: Part 4 – Alginate

Bioprinting 101: Part 4 – Alginate

Written by David

February 14, 2019

Alginate is derived from brown algae Alginate is a polysaccharide distributed widely in cell walls of brown algae. When it bonds with water it typically forms a viscous gum. Alginate absorbs water quickly, which makes it useful as an additive. Alginate can be used as a hydrogel as well. It has very interesting applications. It is a hydrogel consisting of microparticles or in bulk gels combined with nerve growth factor in bioengineering research. It has been used as scaffolding for tissue engineering , as a delivery vehicle for drugs, and as model extracellular matrices for basic biological studies. These applications require tight control of a number of material properties including mechanical stiffness, swelling, degradation, cell attachment, and binding or release of bioactive molecules. The chemical structure of alginate is composed of two types of uronic acid : Mannuronic acid unit (M) and Guluronic acid unit (G). Differences in M/G […]

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