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Bioplotting bone-mimetic 3-D tissue scaffolds with osteogenic effects

Bioplotting bone-mimetic 3-D tissue scaffolds with osteogenic effects

Written by David

February 7, 2019

In bone tissue engineering (BTE), 3-D printing is a reliable and customizable method used to repair bone defects by producing biomimetic tissue scaffolds. In a recent study published online on Tissue Engineering Part A (Mary Ann Liebert, Inc), Qing Li and a team of scientists engineered a biomimetic substitute closest to the natural bone structure and composition for bone grafting . For this work, they used two different types of hydroxyapatite (HA) materials: nanohydroxyapatite (nHA) and deproteinized bovine bone (DBB) dispersed into collagen (CoL) to prepare a bio-ink and engineer composites of nHA/CoL and DBB/CoL as 3-D printed scaffolds. The aesthetic reconstruction of functional alveolar bone is challenging after bone loss due to trauma, inflammation and surgery. Materials scientists can combine tissue engineering and biomaterials to promote alveolar bone regeneration; […]


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