Researchers at Carnegie Mellon University report findings on an advanced nanomaterial-based biosensing platform that detects, within seconds, antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic.
In addition to testing, the platform will help to quantify patient immunological response to the new vaccines with precision. An image of the COVID-19 test chip made by aerosol jet nanoparticle 3D printing. Credit: Advanced Manufacturing and Materials Lab, The College of Engineering at Carnegie Mellon University The results were published this week in the journal Advanced Materials. Carnegie Mellon’s collaborators included the University of Pittsburgh (Pitt) and the UPMC. The testing platform identifies the presence of two of the virus’ antibodies, spike S1 protein and receptor binding domain (RBD), in a very small drop of blood (about 5 microliters). Antibody concentrations can be extremely low and still detected below one picomolar (0.15 nanograms per milliliter). This detection happens through an electrochemical reaction within a handheld microfluidic device which sends results almost immediately to a simple interface on a smart phone. “We utilized the latest advances in materials and manufacturing such as nanoparticle 3D printing to create a device that rapidly detects COVID-19 antibodies,” said Rahul Panat, an associate professor of […]
And you can, too My 3D-printed custom nose bridge. Images courtesy of the author I wear glasses (not pictured above...